Munson Health
Chronic Myelocytic Leukemia

Back to Document

by McCoy K

(CML; Chronic Myeloid Leukemia; Chronic Myelogenous Leukemia; Chronic Granulocytic Leukemia)



Talk with your doctor about the best plan for you. Treatment options include:

Targeted Drug Therapy

Targeted drug therapy inhibits the molecule that triggers the development of leukemia and the gene that is associated with it. This medication is often used in early stages of CML.


Chemotherapy is the use of drugs to kill cancer cells. It may be given by pill, injection, or via a catheter. The drugs enter the bloodstream and travel through the body. While this will focus on cancer cells, some healthy cells are also killed.

High-dose Chemotherapy With Stem Cell Transplant

High doses of chemotherapy are followed by a transplant of stem cells (immature blood cells). These will replace blood-forming cells destroyed by cancer treatment. Stem cells are removed from the blood or bone marrow of the patient or donor. They are then infused into the patient.

Donor Lymphocyte Infusion

Lymphocytes are a type of white blood cell. A donor’s cells are infused into the patient. The cancer cells do not recognize these cells. They do not attack them.


A splenectomy is a surgery to remove the spleen. It may be done if the spleen has become enlarged from the leukemia. It may also be done if other complications develop.


American Cancer Society

The Leukemia and Lymphoma Society

National Cancer Institute



BC Cancer Agency

Canadian Cancer Society



Chronic myelogenous leukemia (PDQ): treatment. National Cancer Institute website. Available at: . Accessed January 29, 2013.

Chronic myeloid leukemia. EBSCO DynaMed website. Available at: Updated December 17, 2012. Accessed January 29, 2013.

Leukemia—chronic myeloid (CML). American Cancer Society website. Available at: . Accessed January 29, 2013.


Revision Information