Munson Health
 
Agranulocytosis

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by Kohnle D

(Granulocytopenia; Granulopenia; Neutropenia)

 

Causes

Agranulocytosis is caused by destruction of white blood cells or by the failure of bone marrow to make enough white blood cells.
With congenital agranulocytosis, these problems are caused by a genetic defect.
With acquired agranulocytosis, these problems may be caused by:
 

Symptoms

Symptoms of agranulocytosis may include:
Symptoms of congenital agranulocytosis may include:
  • Mild infections of skin, mouth, and nose
  • Poor weight gain in children
 

RESOURCES

American Dental Association
http://www.ada.org

National Organization for Rare Disorders, Inc.
http://www.rarediseases.org

 

CANADIAN RESOURCES

The College of Family Physicians of Canada
http://www.cfpc.ca

Health Canada
http://www.hc-sc.gc.ca

 

References


Boulton F, Cooper C, et al. Neutropenia and agranulocytosis in England and Wales: incidence and risk factors. American Journal of Hepatology. 2003 Apr;72(4):248-54.


Neutropenia. EBSCO DynaMed website. Available at: https://dynamed.ebscohost.com/about/about-us. Updated July 11, 2013. Accessed August 20, 2013.

 

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