Munson Health
 
Japanese Encephalitis Vaccine

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by McCoy K
 

What Is Japanese Encephalitis?

Japanese encephalitis is a virus that is spread by mosquitoes. It can cause swelling of the brain. It also affects the central nervous system. Japanese encephalitis can cause severe complications, like long-term neurological disability and death.
People get Japanese encephalitis when they are bitten by a mosquito infected with the virus. Japanese encephalitis is a common cause of viral encephalitis in Asia. It can be prevented by vaccines.
Many people with the infection may have no symptoms. If symptoms develop, they can include:
  • Fever
  • Chills
  • Tiredness
  • Headache
  • Neck stiffness
  • Nausea
  • Vomiting
  • Confusion
  • Restlessness
  • Brain damage
  • Coma
  • Tremors
  • Convulsions, especially in infants
Symptoms of Japanese encephalitis usually appear 5-15 days after the bite from an infected mosquito.
There is no specific treatment for this condition. Care for people with the disease is aimed at easing symptoms.
 


WHERE CAN I GET MORE INFORMATION?

Centers for Disease Control and Prevention
http://www.cdc.gov

Immunization Action Coalition
http://www.immunize.org

 

References


Clinical trials sites in the United States for Ixiaro in children under 17. Centers for Disease Control and Prevention website. Available at http://www.cdc.gov/ncidod/dvbid/jencephalitis/resources/UpdtJEVaccChildren%5FWeb%5FTable1.pdf. Accessed November 19, 2013.


Dubischar-Kastner K, Kaltenboeck A, et al. Safety analysis of a Vero cell culture-derived Japanese encephalitis vaccine, IXIARO (IC51), in 6 months of follow-up. Vaccine. 2010;28(39):6463-6469.


Fischer M, Lindsey N, et al; Centers for Disease Control and Prevention (CDC). Japanese encephalitis vaccines: recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep. 2010;59(RR-1):1-27.


Halstead SB, Thomas SJ. New Japanese encephalitis vaccines: alternatives to production in mouse brain. Expert Rev Vaccines. 2011;10(3):355-364.


Halstead SB, Thomas SJ. Japanese encephalitis: new options for active immunization. Clin Infect Dis. 2010;50(8):1155-1164.


Japanese encephalitis. EBSCO DynaMed website. Available at: https://dynamed.ebscohost.com/about/about-us. Updated May 22, 2013. Accessed November 19, 2013.


Japanese encephalitis vaccine: What you need to know. Centers for Disease Control and Prevention website. Available at: http://www.immunize.org/vis/je%5Fixiaro.pdf. Updated December 7, 2011. Accessed November 19, 2013.


Lehtinen VA, Huhtamo E, Siikamäki H, Vapalahti O. Japanese encephalitis in a Finnish traveler on a two-week holiday in Thailand. J Clin Virol. 2008;43(1):93-95.


Wilder-Smith A, Halstead SB. Japanese encephalitis: update on vaccines and vaccine recommendations. Curr Opin Infect Dis. 2010;23(5):426-431.

 

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