Munson Health
 
Spherocytosis

Back to Document

by Kohnle D

(Congenital Spherocytic Anemia; Hereditary Spherocytosis)

 

Symptoms

Symptoms include:
  • Jaundice
  • Pallor
  • Shortness of breath
  • Fatigue
  • Weakness
  • In children, irritability and moodiness
  • Hemolytic anemia
  • Gallstones
 

Treatment

Talk with your doctor about the best treatment plan for you. Treatment options include:

Surgery

Surgical removal of the spleen can cure the anemia. The abnormal shape of blood cells remain, but the blood cells are no longer destroyed in the spleen.
Currently, meningococcal , Haemophilus , and pneumococcal vaccines are administered several weeks before splenectomy. Lifetime penicillin prophylaxis is recommended after surgery to prevent dangerous infections. The surgery is not recommended for children under the age of five. There is a lifetime risk of serious and potentially life threatening infections.
Currently, meningococcal , Haemophilus , and pneumococcal vaccines are administered several weeks before splenectomy. Lifetime penicillin prophylaxis is recommended after surgery to prevent dangerous infections. The surgery is not recommended for children under the age of five. There is a lifetime risk of serious and potentially life threatening infections.
 

RESOURCES

Blood Disorders
Centers for Disease Control and Prevention
http://www.cdc.gov/ncbddd/blooddisorders/index.html/

Health Canada
http://www.hc-sc.gc.ca/index%5Fe.html/

 

CANADIAN RESOURCES

Health Canada
http://www.hc-sc.gc.ca/index%5Fe.html/

Public Health Agency of Canada
http://www.phac-aspc.gc.ca/chn-rcs/index-eng.php/

 

References


Baylor College of Medicine. Hereditary spherocytosis. Baylor College of Medicine website. Available at: http://www.bcm.edu/pediatrics/documents/4112.pdf . Accessed June 27, 2007.


Delaunay J. The molecular basis of hereditary red blood cell membrane disorders. Blood Rev . 2007;21:1-20.


DynaMed Editorial Team. Hereditary spherocytosis. EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed/what.php . Updated February 2, 2010. Accessed November 11, 2010.


Mayo Clinic. Treatment of anemia. Mayo Clinic website. Available at: http://www.mayoclinic.org/anemia/index.html . Accessed June 27, 2007.

 

Revision Information