Munson Health
 
Crohn's Disease

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by Carson-DeWitt R

(CD; Regional Enteritis)

 

Definition

Crohn's disease is a severe, chronic inflammatory bowel disease. It causes inflammation, ulcers, and bleeding in the digestive tract. It usually affects the end portion of the small intestine called the ileum. However, any part of the digestive tract can be affected, from the mouth to the anus.
Small Intestine
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Causes

The cause of Crohn's disease is not known. Inflammatory bowel diseases, such as ulcerative colitis and Crohn's disease, seem to run in some families. Some researchers think that it is due to a reaction to a virus or bacteria. The immune system overreacts and causes damage to the intestines.
 

Symptoms

Symptoms include:
  • Diarrhea
  • Abdominal cramps and pain
  • Rectal bleeding
  • Weight loss
  • Fatigue, weakness
  • Nausea
  • Fever
  • Mouth sores
  • Sores, abscesses in the anal area
 

RESOURCES

American Gastroenterological Association
http://www.gastro.org

Crohn's and Colitis Foundation of America
http://www.ccfa.org

 

CANADIAN RESOURCES

Crohn's and Colitis Foundation of Canada
http://www.ccfc.ca

Health Canada
http://www.hc-sc.gc.ca

 

References


Crohn's disease. National Institute of Diabetes and Digestive and Kidney Diseases website. Available at: http://digestive.niddk.nih.gov/ddiseases/pubs/crohns/index.aspx. Updated January 10, 2013. Accessed January 6, 2014.


Hou JK, Abraham B, El-Serag H. Dietary intake and risk of developing inflammatory bowel disease: a systematic review of the literature. Am J Gastroenterol. 2011;106(4):563-573.


Inflammatory bowel disease. American Gastroenterological Society website. Available at: http://www.gastro.org/patient-center/digestive-conditions/inflammatory-bowel-disease. Accessed January 6, 2014.


What is Crohn's disease? Crohn's and Colitis Foundation of America website. Available at: http://www.ccfa.org/what-are-crohns-and-colitis/what-is-crohns-disease/. Accessed January 6, 2014.


10/2/2009 DynaMed's Systematic Literature Surveillance. http://www.ebscohost.com/dynamed: FDA approves new drug to treat psoriasis. US Food and Drug Administration website. Available at: http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm183851.htm. Published September 25, 2009. Accessed January 6, 2014.


11/25/2013 DynaMed's Systematic Literature Surveillance. http://www.ebscohost.com/dynamed: Khalili H, Ananthakrishnan A, et al. Physical activity and risk of inflammatory bowel disease: prospective study from the Nurses' Health Study cohorts. BMJ 2013;347:f6633.

 

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