Munson Health
 
Creutzfeldt-Jakob Disease

Back to Document

by Badash M

(Subacute Spongiform Encephalopathy; CJD)

 

Definition

CJD can be categorized into different subtypes:
  • Sporadic CJD—most common type; usually affects people aged 50 years and older
  • Familial CJD—an inherited form of the disease
  • Iatrogenic CJD—contracted through medical procedures, such as injections of growth hormone, or receipt of corneal transplants or dura mater implants from affected donors
Variant CJD (vCJD) is a different prion disease caused by eating contaminated beef products. This variant form differs from other forms of CJD because it affects younger people and has a longer average time course.
 

Diagnosis

Your doctor will ask about your symptoms and medical history. A physical exam will be done.
CJD is a difficult disease to diagnose. There is no single test to detect it. Tests may include:
Imaging tests take pictures of your internal body structures. Imaging tests may include:
In many cases, final diagnosis requires an autopsy after death.
MRI Scan of the Brain
MRI of the Brain
Copyright © Nucleus Medical Media, Inc.
 

RESOURCES

Creutzfeldt-Jakob Disease Foundation, Inc.
http://www.cjdfoundation.org

National Institute of Neurological Disorders and Stroke
http://www.ninds.nih.gov

 

CANADIAN RESOURCES

Health Canada
http://www.hc-sc.gc.ca

Public Health Agency of Canada
http://www.phac-aspc.gc.ca

 

References


About CJD (Creutzfeldt-Jakob disease, classic). Centers for Disease Control and Prevention website. Available at: http://www.cdc.gov/ncidod/dvrd/cjd/index.htm. Updated November 15, 2012. Accessed June 27, 2013.


Brown K, Mastrianni JA. The prion diseases. J Geriatr Psychiatry Neurol. 2010;23(4):277-298.


CDC's diagnostic criteria for Creutzfeldt-Jakob Disease (CJD), 2010. Centers for Disease Control and Prevention website. Available at: http://www.cdc.gov/ncidod/dvrd/cjd/index.htm. Updated August 26, 2010. Accessed June 27, 2013.


Creutzfeldt-Jakob disease. EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed/what.php. Updated March 5, 2012. Accessed June 27, 2013.


Creutzfeldt-Jakob disease fact sheet. National Institute of Neurological Disorders and Stroke website. Available at: http://www.ninds.nih.gov/disorders/cjd/detail%5Fcjd.htm. Updated June 6, 2013. Accessed June 27, 2013.


Mastrianni JA. The genetics of prion disease. Genet Med. 2010;12(4):187-195.


Patry D, Curry B, et al. Creutzfeld-Jakob disease (CJD) after blood product transfusion from a donor with CJD. Neurology. 1998;50(6):1872-1873.


Rinne ML, McGinnis SM, et al. Clinical problem-solving. A startling decline. N Engl J Med. 2012;366(9):836-842.

 

Revision Information