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Anaphylaxis

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by Shah PS

(Anaphylactic Reaction; Severe Allergic Reaction)

 

Causes

Substances that cause anaphylaxis are often called allergens or triggers. Common triggers include:
Allergic Reaction to Medication (Hives)
Hives Medication
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Some triggers, like dyes used in x-ray procedures, can cause a reaction similar to anaphylaxis.
 

Risk Factors

Anyone can have anaphylaxis. Factors that may increase your risk of anaphylaxis include:
 

Symptoms

The symptoms of anaphylaxis usually occur within minutes after exposure to an allergen, but can occur hours later. Symptoms may be mild or severe, including death. They include:
  • Hives and itching
  • Warmth or redness of skin
  • Swelling, redness, stinging or burning, especially on the face, mouth, eyes, or hands
  • Lightheadedness and pale/blue skin color
  • Chest tightness, shortness of breath, difficulty breathing, and wheezing
  • Nausea, vomiting, cramping, diarrhea , or abdominal pain
  • Loss of consciousness
 

RESOURCES

American Academy of Allergy, Asthma, and Immunology
http://www.aaaai.org

Food Allergy Research and Education
http://www.foodallergy.org

 

CANADIAN RESOURCES

Allergy Asthma Information Association
http://aaia.ca

Calgary Allergy Network
http://www.calgaryallergy.ca

 

References


Anaphylaxis. Am Fam Physician. 2003 Oct 1;68(7):1339-1340. Available at: http://www.aafp.org/afp/20031001/1339ph.html. Accessed August 19, 2014.


Anaphylaxis. EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed. Updated April 14, 2014. Accessed September 10, 2014.


Kay AB. Allergy and allergic diseases–second of two parts. N Engl J Med. 2001;344:109-113.


Lieberman P, Kemp SF, et al. The diagnosis and management of anaphylaxis: An updated practice parameter. J Allergy Clin Immunol. 2005 Mar;115(3 Suppl 2):S483-523.


Pumphrey R. Anaphylaxis: can we tell who is at risk of a fatal reaction?. Curr Opin Allergy Clin Immunol. 2004; 4:285.


Sampson, HA, Munoz-Furlong, A, et al. Second symposium on the definition and management of anaphylaxis: summary report—Second National Institute of Allergy and Infectious Disease/Food Allergy and Anaphylaxis Network symposium. J Allergy Clin Immunol. 2006;117:391.


Simons E. Anaphylaxis. J Allergy Clin Immunol. 2010;125: S161-81.


Winbery SL, Lieberman PL. Anaphylaxis. Immunol Allergy Clin North Am. 1995;15:447.

 

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