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Aluminum Toxicity

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by McCoy K

(Aluminum Poisoning)

 

Symptoms

  • Confusion
  • Muscle weakness
  • Bone pain, deformities, and fractures
  • Seizures
  • Speech problems
  • Slow growth—in children
Complications may include:
  • Lung problems
  • Nervous system problems causing difficulty with voluntary and involuntary actions
  • Bone diseases
  • Brain diseases and disorders
  • Anemia
  • Impaired iron absorption
Red Blood Cells
Red blood cells new
These vital cells transport oxygen through the body. Symptoms of aluminum toxicity such as anemia and impaired iron absorption decrease the number of red blood cells.
Copyright © Nucleus Medical Media, Inc.
 

RESOURCES

Agency for Toxic Substances and Disease Registry
http://www.atsdr.cdc.gov

Environmental Protection Agency
http://www.epa.gov

 

CANADIAN RESOURCES

Guide to Less Toxic Products
Environmental Health Association of Nova Scotia
http://www.lesstoxicguide.ca

Poison Control Centers for Canada
Association of the Chemical Profession of Ontario
http://www.acpo.on.ca

 

References


Andia JB. Aluminum toxicity: its relationship with bone and iron metabolism. Nephrol Dial Transplant. 1996; 11 Suppl 3:69-73.


Bia MJ, Cooper K, et al. Aluminum induced anemia: pathogenesis and treatment in patients on chronic dialysis. Kidney Int. 1989 Nov;36(5):852-8.


Delmez J, Weerts C, et al. Accelerated removal of deferoxamine mesylate-chelated aluminum by charcoal hyperfusion in hemodialysis patients. Am J Kidney Disease. 1989 Apr;13(4):308-11.


D’Haese PC, Couttenye MM, et al. Use of the low-dose desferrioxamine test to diagnose and differentiate between patients with aluminum-related bone disease, increased risk for aluminum toxicity, or aluminium overload. Nephrol dial Transplant. 1995;10:1874-84.


Goldman L, Ausiello D, eds. Cecil Textbook of Internal Medicine. 23rd ed. Philadelphia, PA: Saunders; 2008.


Kawahara M. Effects of aluminum on the nervous system and its possible link with neurodegenerative diseases. J Alzheimers Dis . 2005;8:171-82.


Krewski D, Yokei RA, Nieboer E et al: Human health risk assessment for aluminium, aluminium oxide, and aluminium hydroxide. J Toxicol Environ Health b Crit Rev . 2007:10 supl 1: 1-269


Malluche HH. Aluminum and bone disease in chronic renal failure. Nephrol dial Transplant . 2002; 17:21-24.


Marx JA, et al. Rosen's Emergency Medicine .7th ed. St. Louis, MO: Mosby, Inc.; 2009.


Molloy DW, Standish TI, Nieboer E et al: Effects of acute exposure to aluminum on cognition in humans. J Toxicol Environ Health . A 2007: 70:2011-9


Toxic substances portal: Aluminum. Centers for Disease Control and Prevention website. Available at: http://www.atsdr.cdc.gov/toxfaqs/tf.asp?id=190&tid=34#bookmark08 . Updated October 27, 2011. Accessed April 2, 2013.

 

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