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Septic Shock

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by McCoy K
 

Definition

Sepsis is a systemic inflammatory response to a severe infection. The inflammatory response triggers a rapid cascade of events, such as leaking blood vessels and impaired blood flow.
Severe sepsis is associated with a drop in blood pressure. Low blood pressure reduces the amount of oxygen and nutrients going to the body's organs. This drop causes damage the body's major organs.
Septic shock occurs when adequate blood pressure can't be restored despite treatment with IV fluids. Septic shock may lead to multiple organ failure and death.
 

RESOURCES

Centers for Disease Control and Prevention
http://www.cdc.gov

Society of Critical Care Medicine
http://www.sccm.org

 

CANADIAN RESOURCES

Canadian Association of Emergency Physicians
http://www.caep.ca

Health Canada
http://www.hc-sc.gc.ca

 

References


Behrman RE, et al. Nelson Textbook of Pediatrics. 18th ed. Philadelphia, PA: Saunders; 2007.


Dellinger RP, Levy MM, et al. Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2012. Crit Care Med. 2013;41(2):580-637.


Goldman L, Ausiello D, eds. Cecil Textbook of Internal Medicine. 23rd ed. Philadelphia, PA: Saunders; 2008.


Marx JA, et al. Rosen's Emergency Medicine.7th ed. St. Louis, MO: Mosby, Inc.; 2009.


Sepsis and septic shock. Merck Manual of Diagnosis and Therapy website. Available at: http://www.merckmanuals.com/professional/critical%5Fcare%5Fmedicine/sepsis%5Fand%5Fseptic%5Fshock/sepsis%5Fand%5Fseptic%5Fshock.html?qt=septic shock&alt=sh. Updated July 2013. Accessed December 30, 2013.


Sepsis fact sheet. National Institute of General Medical Sciences website. Available at: http://www.nigms.nih.gov/Education/Pages/factsheet%5Fsepsis.aspx. Updated November 2012. Accessed December 30, 2013.


Sepsis in adults. EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed. Updated October 28, 2013. Accessed December 30, 2013.


Sepsis treatment in adults. EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed. Updated December 28, 2013. Accessed December 30, 2013.

 

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