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Adrenal Crisis

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by McCoy K

(Acute Adrenocortical Insufficiency)

 

Causes

Adrenal crisis may be caused by:
  • Rapid withdrawal from steroid therapy
  • Sepsis—a bloodstream infection
  • Surgical stress
  • Adrenal apoplexy, infarction, or surgical removal—bleeding into the adrenal glands
  • Pituitary necrosis—damage to pituitary tissue from hemorrhage, infarction, surgery, or trauma
  • Thyroid hormone replacement in someone with adrenal insufficiency
 

RESOURCES

American Association of Clinical Endocrinologists
http://www.aace.com

Endocrine and Metabolic Diseases Information Service
http://www.endocrine.niddk.nih.gov

 

CANADIAN RESOURCES

Canadian Association of Emergency Physicians
http://www.caep.ca

Canadian Institute for Health Information
http://www.cihi.ca

 

References


Acute adrenocortical insufficiency. DynaMed website. Available at: https://dynamed.ebscohost.com/about/about-us. Updated May 29, 2013. Accessed July 15, 2013.


Adrenal crisis causes death in some people treated with human growth hormone. National Institute of Diabetes and Digestive and Kidney Diseases website. Available at: http://www.endocrine.niddk.nih.gov/pubs/creutz/alert.htm. Published September 24, 2012. Accessed July 15, 2013.


Adrenal insufficiency and Addisons disease. National Institute of Diabetes and Digestive and Kidney Diseases website. Available at: http://www.endocrine.niddk.nih.gov/pubs/addison/addison.aspx. Updated April 6, 2012. Accessed July 15, 2013.


Omori K, Nomura K, et al. Risk factors for adrenal crisis in patients with adrenal insufficiency. Endocrine J. 2003; 50:745-752.


Thomas Z: an update on the diagnosis of adrenal insufficiency and the use of corticotherapy in critical illness. Ann Pharmacotherapy. 2007:41:1456-1465


Todd GRG, Acerini CL, et al. Survey of adrenal crisis associated with inhaled corticosteroids in the United Kingdom. Arch. Dis Child. 2002; 87:457-461.

 

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