Munson Health
 
Medications for Endometriosis

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The information provided here is meant to give you a general idea about each of the medications listed below. Only the most general side effects are included, so ask your healthcare provider if you need to take any special precautions. Use each of these medications as recommended by your healthcare provider, or according to the instructions provided. If you have further questions about usage or side effects, contact your healthcare provider.

Prescription Medications

  • Leuprolide Acetate (Lupron Depot)
  • Nafarelin Acetate (Synarel)
  • Goserelin Acetate (Zoladex)
  • Danazol (Danocrine, Cyclomen)
  • Medroxyprogesterone Acetate (Depo-Provera)
  • Norethindrone (Aygestin)
  • Norlutate
  • Progestin-containing Intrauterine Device: Levonorgestrel-releasing intrauterine system (Progestasert, Mirena)
  • Combined estrogen/progesterone oral contraceptives
  • Anasrozole
  • Letrozole
  • Exemestrane

Over-the-Counter Medications

  • Ibuprofen (Advil, Motrin)
  • Naproxen sodium (Aleve)

Prescription Medications

 

References


Abou-Setta AM, Al-Inany HG, et al. Levonorgestrel-releasing intrauterine device (LNG-IUD) for symptomatic endometriosis following surgery. Cochrane Database of Systematic Reviews. 2006;(4):CD005072.


Allen C, Hopewell S, et al. Non-steroidal anti-inflammatory drugs for pain in women with endometriosis. Cochrane Database of Systematic Reviews. 2005;(4):CD004753.


Appleyard TL, Mann CH, et al. Guidelines for the management of pelvic pain associated with endometriosis: a systematic appraisal of their quality. BJOG. 2006;113(7):749-757.


Attar E, Bulun SE. Aromatase inhibitors: the next generation of therapeutics for endometriosis? Fertil Steril. 2006;85:1307-1318.


The Endometriosis Association website. Available at: http://www.endometriosisassn.org. Accessed March 1, 2006.


Endometriosis Research Center website. Available at: http://www.endocenter.org. Accessed March 1, 2006.


Farquhar C, Sutton C. The evidence for the management of endometriosis. Curr Opinion in Obstet & Gynecol. 1998;10(4):321-332.


Gabbe, SG. Obstetrics: Normal and Problem Pregnancies. 5th ed. London: Churchill Livingstone, 2007.


Katz VL. Comprehensive Gynecology. 5th ed. St. Louis: Mosby, 2007.


Kistner’s Gynecology and Women’s Health. 7th ed. Mosby-Year Book; 1999.


Medical Management of Endometriosis. The American College of Obstetricians and Gynecologists, Practice Bulletin No. 11. Dec 1999.


Moore J, Kennedy S, et al. Modern combined oral contraceptives for pain associated with endometriosis. Cochrane Database of Systematic Reviews. 2000;(2):CD001019.


National Institute of Child Health and Human Development website. Available at: http://www.nichd.nih.gov. Accessed March 1, 2006.


National Women’s Health Resource Center website. Available at: http://www.healthywomen.org. Accessed March 1, 2006.


Rakel R. Textbook of Family Medicine 2007. 7th ed. Philadelphia: Saunders Elsevier, 2009.


Rakel RE, Bope ET. Conn's Current Therapy. 60th ed. Philadelphia: Saunders Elsevier, 2009.


Razzi S, Fava A, et al. Treatment of severe recurrent endometriosis with an aromatase inhibitor in a young ovariectomised woman. BJOG. 2004;111:182-184.


Selak V, Farquhar C, et al. Danazol for pelvic pain associated with endometriosis [update]. Cochrane Database of Systematic Reviews. 2001;(4):CD000068.


Shippen E, West WJ. Successful treatment of severe endometriosis in two premenopausal women with an aromatase inhibitor. Fertil Steril. 2004;81:1395-1398.


Surrey ES, Hornstein MD. Prolonged GnRH agonist and add-back therapy for symptomatic endometriosis: long-term follow-up. Obstet & Gynecol. 2002;99(5):709-719.


Vercellini P, Cortesi I, et al. Progestins for symptomatic endometriosis: a critical analysis of the evidence. Fertility & Sterility. 1997;68(3):393-401.


Yap C, Furness S, et al. Pre and post operative medical therapy for endometriosis surgery. Cochrane Database of Systematic Reviews. 2004;(3):CD003678.


3/12/2010 DynaMed's Systematic Literature Surveillance http://www.ebscohost.com/dynamed/what.php: Seracchioli R, Mabrouk M, et al. Long-term cyclic and continuous oral contraceptive therapy and endometrioma recurrence: a randomized controlled trial. Fertil Steril. 2010;93(1):52-56.

 

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