Munson Health
 
Medications for End-stage Renal Disease (ESRD)

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by Wood D
 
The information provided here is meant to give you a general idea about each of the medications listed below. Only the most general side effects are included. Ask your doctor if you need to take any special precautions. Use each of these medications only as recommended by your doctor, and according to the instructions provided. If you have further questions about usage or side effects, contact your doctor.
If you have high blood pressure , hyperlipidemia , or diabetes , medications will likely be ordered to control these conditions. Leakage of protein from the urine is treated with two drugs used in the treatment of high blood pressure: angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs). In addition, medications may be needed to treat complications of kidney disease. There are no medications to cure or reverse kidney failure.

Prescription Medications

  • Sensipar
  • Furosemide (Lasix)
  • Bumetanide (Bumex)
  • Renagel
  • Epogen
  • Procrit

Prescription Medications

  Cinacalcet HCL
  • Common name: Sensipar
In chronic renal disease, a disturbance in calcium, phosphate, and vitamin D metabolism leads to a condition called secondary hyperparathyroidism . It is characterized by abnormally high levels of parathyroid hormone (PTH) in the blood. The high PTH levels lead to uremic bone disease. Cinacalcet HCL is effective in lowering the elevated PTH levels in chronic renal failure patients. It is taken by mouth.
Possible side effects include:
  • Nausea
  • Vomiting
  • Transient low blood calcium level
Diuretics
  • Furosemide (Lasix)
  • Bumetanide (Bumex )
Diuretics help rid the body of excess fluid. These medications are sometimes referred to as water pills. Diuretics may be taken by mouth or, in some cases, by injection.
Possible side effects include:
  • Lightheadedness
  • Mouth dryness
  • Weakness
  • Frequent urination
 

References


Chronic kidney disease. EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed. Updated April 22, 2013. Accessed July 2, 2013.


Coladonato JA. Control of hyperphosphatemia among patients with ESRD. J Am Soc Nephro. 2005;16:S107-114


Malluche HH, Mawad H, et al. The importance of bone health in end-stage renal disease: out of the frying pan, into the fire? Nephrol Dial Transplant. 2004;19:9-13.


End-stage renal disease. National Institute of Diabetes & Digestive & Kidney Diseases website. Available at: http://www2.niddk.nih.gov/Research/ScientificAreas/Kidney/KEB.htm. Updated September 15, 2010. Accessed July 2, 2013.


Torres PU. Cinacalcet HCL: a novel treatment for secondary hyperparathyroidism caused by chronic kidney disease. J Ren Nutr. 2006;16:253-258.


Yu HT. Progression of chronic renal failure. Arch Int Med. 2003;163:1417-1429.

 

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