Munson Health
Acetaminophen Poisoning

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by McCoy K

(Paracetamol Poisoning; Acetaminophen Overdose; Paracetamol Overdose)



At first, a person with acetaminophen poisoning may have no symptoms.
When symptoms develop, they can include:
Jaundice Skin from Damaged Liver
Jaundice adult with label
Healthy liver on the left compared to diseased liver on the right that has caused jaundice of the skin.
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American Academy of Pediatrics

American Association of Poison Control Centers



Canadian Institute for Health Information

Children's Safety—Canadian Poison Control Centers



Recognition and management of acute medication poisoning. American Academy of Family Physicians website. Available at: Accessed November 7, 2012.

Acetaminophen poisoning. DynaMed website. Available at: Updated August 3, 2012. Accessed November 7, 2012.

The FDA Acetaminophen Advisory Committee Meeting. What is the future of acetaminophen in the United States? The perspective of a committee member. Clinical Toxicology (Philadelphia). 2009;47(8):784-789.

Ferner RE, Dear JW, et al. Management of paracetamol poisoning. BMJ. 2011;342:d2218.

Goldman L, Ausiello D, eds. Cecil Textbook of Internal Medicine. 23rd ed. Philadelphia, PA: Saunders; 2008

Lavonas EJ, Reynolds KM, et al. Therapeutic acetaminophen is not associated with liver injury in children: a systematic review. Pediatrics. 2010 ;126(6):e1430-1444.

Marx J, et al. Rosen's Emergency Medicine. 7th ed. St. Louis, MO: Mosby, Inc; 2009.

Vassallo S, Khan AN, et al. Use of the Rumack-Matthew nomogram in cases of extended-release acetaminophen toxicity. Ann Intern Med. 1996;125(11):940.

8/8/2011 DynaMed's Systematic Literature Surveillance McNeil Consumer Healthcare announces plans for new dosing instructions for Tylenol products. Johnson & Johnson website. Available at: Accessed August 8, 2011.


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