Munson Health
 
Medications for Scleroderma

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by Carson-DeWitt R
 
The information provided here is meant to give you a general idea about each of the medications listed below. Only the most general side effects are included, so ask your doctor if you need to take any special precautions. Use each of these medications as advised by your doctor, or according to the instructions provided. If you have further questions about usage or side effects, contact your doctor.
There are no medications available to cure or halt the progression of scleroderma. Scleroderma is treated on a symptom-by-symptom basis.

Over-the-counter Medications

Prescription Medications

  Calcium-channel Blockers
Calcium-channel blockers can reduce the symptoms of Raynaud’s phenomenon by relaxing blood vessels. This allows better blood circulation through the fingers, toes, and the tip the of nose. When exposed to cold, you’ll have less trouble with skin blanching and less numbness and tingling. Use of calcium-channel blockers can reduce the chance of developing sores or ulcers on your fingertips.
Calcium-channel blockers may also be given to treat high blood pressure.
Possible side effects include:
  • Low blood pressure
  • Constipation
  • Nausea
  • Lightheadedness
  • Headache
  • Swelling
  H-2 Blockers
Possible side effects include:
  • Lighheadedness
  • Confusion
  • Headache
  • Diarrhea
 

References


Durand F, Staumont D, Bonnevalle A, Hachulla E, Hatron PY, Thomas P. Ultraviolet A1 phototherapy for treatment of acrosclerosis in systemic sclerosis: controlled study with half-side comparison analysis. Photodermatol Photoimmunol Photomed. 2007;23(6):215-221.


Iloprost. Pulmonary Hypertension Association website. Available at: http://www.phassociation.org/Patients/Treatment/Iloprost. Accessed May 20, 2014.


Kreuter A, Hyun J, Stücker M, Sommer A, Altmeyer P, Gambichler T. A randomized controlled study of low-dose UVA1, medium-dose UVA1, and narrowband UVB phototherapy in the treatment of localized scleroderma. J Am Acad Dermatol. 2006;54(3):440-447.


Scleroderma. National Institute of Arthritis and Musculoskeletal and Skin Diseases website. Available at: http://www.niams.nih.gov/Health%5FInfo/Scleroderma/default.asp. Updated August 2012. Accessed May 20, 2014.


Systemic sclerosis. EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed. Updated March 4, 2014. Accessed May 20, 2014.


Thompson AE, Shea B, Welch V, Fenlon D, Pope JE. Calcium-channel blockers for Raynaud's phenomenon in systemic sclerosis. Arthritis Rheum. 2001;44(8):1841-1847.


What is scleroderma? Scleroderma Foundation website. Available at: http://www.scleroderma.org/site/PageNavigator/patients%5Fwhatis.html. Accessed May 20, 2014.


Zachariae H, Halkier-Sorensen L, Bjerring P, Heickendorff L. Treatment of ischaemic digital ulcers and prevention of gangrene with intravenous iloprost in systemic sclerosis. Acta Dermato-Venereologica. 1996;76:236-238.


3/1/2010 DynaMed's Systematic Literature Surveillance http://www.ebscohost.com/dynamed: Maalox Total Relief and Maalox liquid products: medication use errors. US Food and Drug Administration website. Available at: http://www.fda.gov/Safety/MedWatch/SafetyInformation/SafetyAlertsforHumanMedicalProducts/ucm200672.htm. Updated February 18, 2010. Accessed March 20, 2014.

 

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