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Guillain-Barr Syndrome

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by Badash M

(Acute Inflammatory Demyelinating Polyradiculoneuropathy; Acute Inflammatory Demyelinating Polyneuropathy; Acute Idiopathic Polyneuritis; Acute Inflammatory Polyneuropathy; Acute Autoimmune Neuropathy; Idiopathic Polyneuritis; AIDP)

 

Diagnosis

You may have a lumbar puncture, also called a spinal tap . For this test, a needle is inserted into your lower back to remove a sample of cerebrospinal fluid for testing. If high levels of protein are detected, and there is no infection, this is an indication that you may have Guillain-Barré syndrome. Electrodiagnostic studies are usually done, which test the electrical conduction in the peripheral nerves and help differentiate Guillain-Barré from other disorders with similar symptoms.
 

Treatment

Plasmapheresis

During plasmapheresis , blood is removed from your body and passed through a machine that separates blood cells. The separated cells are then returned to your body with new plasma. This procedure may help shorten the course and severity of Guillain-Barré syndrome.

High-dose Immunoglobulin Therapy

Intravenous infusion with immunoglobulin (IVIg) may help reduce the severity of a Guillain-Barré attack. Immunoglobulins are proteins that are naturally produced by the body’s immune system.

Mechanical Ventilation

In 30% of cases, muscles necessary for breathing become paralyzed. This is treated with immediate emergency support from a mechanical ventilator.

Pain Control

Your doctor may prescribe medication to reduce the pain. These may include nonsteroidal anti-inflammatory drugs, gabapentin, carbamezepine, or narcotic analgesics.
If you are diagnosed with Guillain-Barré syndrome, follow your doctor's instructions .
If you are diagnosed with Guillain-Barré syndrome, follow your doctor's instructions .
 

RESOURCES

Guillain-Barré Syndrome Foundation International
http://www.gbs-cidp.org/

National Institute of Neurological Disorders and Stroke
http://www.ninds.nih.gov

 

CANADIAN RESOURCES

Canadian Institute for Health Information
http://www.cihi.ca/

Health Canada
http://www.hc-sc.gc.ca/

 

References


Amyotrophic lateral sclerosis. EBSCO Publishing DynaMed website. Available at: Available at: http://www.ebscohost.com/dynamed . Updated January 31, 2008. Accessed February 23, 2008.


Bradley WG, Daroff RB. Neurology in Clinical Practice . Philadelphia, PA: Butterworth Heinemann Publishing; 2004.


Brown B Amyotrophic lateral sclerosis. In: Gilman S, ed. MedLink Neurology. San Diego, CA: MedLink Corporation. Available at: http://www.medlink.com . Accessed February 23, 2008.


Goetz S. Acute inflammatory demyelinating polyradiculoneuropathy. In: Clinical Neurology. 3rd ed. Philadelphia, PA: Saunders; 2007.


National Institute of Neurological Disorders and Stroke website. Available at: http://www.ninds.nih.gov .


Textbook of Clinical Neurology . WB Saunders Company; 1999.


Vucic S, Kiernan MC, Cornblath DR. Guilainn-Barre: an update. J Clinical Neuroscience . 2009;16(6):733-741.

 

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