Munson Health
Hypoxic Ischemic Encephalopathy

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by Kohnle D

(Cerebral Hypoxia; HIE)



There are a variety of causes of HIE. Any injury and many health conditions can cause a lack of oxygen to the brain. Some common causes are:


Treatment depends on the underlying cause of the condition, as well as the severity of the damage to the brain. Treatment options include:


In most cases, HIE is sudden and cannot be prevented. CPR may be given to prevent significant or long-term brain damage after the oxygen supply has been reduced.


Brain Injury Association of America

National Institute of Neurological Disorders and Stroke



Health Canada

Ontario Brain Injury Association



Brain injury secondary to carotid intervention [review]. J Endovasc Ther. 2007;14:219-231.

Hypoxic ischemic encephalopathy (HIE). Neurographics website. Available at: Accessed August 1, 2013.

Itoo BA, Al-Hawsawi ZM, Khan AH. Hypoxic ischemic encephalopathy. Incidence and risk factors in North Western Saudi Arabia. Saudi Medical Journal. 2003;24:147-153.


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